ABSTRACT
Vaccine acceptance is essential to complete the vaccination program and reach community-based immunity. On the other hand, vaccine hesitancy is an important limiting factor, particularly among healthcare workers and mainly in lower-income nations. The objective of this study is to evaluate the level of vaccination among healthcare workers. A questionnaire was conducted in which healthcare workers were involved. In this work 528 healthcare workers were involved (7 physicians, 57 dentists, 22 pharmacists, 5 nurses and 9 other jobs). Our findings showed that 90% of participants were infected before vaccination while 10% had no history of infection before vaccination. While 93 % of participants received vaccine only 7% did not. Regarding the number of jabs, 7% of participants received one jab, 79% received two jabs and 14% received three jabs. The incidence of COVID-19 infection was dramatically lower among vaccinated health workers which was accounting for 38% with protection against infection (62% of participants). About 28% of participants who rejected vaccination they did so because they have chronic diseases, 15% rejected vaccination because they are pregnant women, 17% rejected vaccination because of its adverse effects while about 14% did not receive vaccine because of carelessness. Overall, our results show that the vaccination status among healthcare workers in Najaf is satisfying.Copyright © 2023, Colegio de Farmaceuticos de la Provincia de Buenos Aires. All rights reserved.
ABSTRACT
Background: Multiple diseases of inflammatory pathology have been successfully managed using the anti-IL-6 receptor monoclonal antibody. In addition, this drug has been shown to improve the outcomes in patients with COVID-19 pneumonia all over the world. Nevertheless, several reports have raised the issue of conflicting results with respects to outcomes of patients with severe cases of COVID-19 receiving tocilizumab form of treatment. Aim of the study: The current study was planned and conducted to assess the outcomes of patients receiving tocilizumab in addition to standard COVID-19 treatment in comparison with group of patients receiving only standard form of treatment. Patients and methods: The current interventional study was conducted in Al-Diwaniyah Teaching Hospital, Al-Diwaniyah Province, Iraq starting from June the 15th 2021 through February 2022. The study included 100 patients who were admitted to the intensive care unit in the hospital because of severe presentation attributed to COVID-19 pneumonia. The age range of those patients was from 18 to 80 years and they were randomly allocated into two groups, the first group (n = 50) received standard treatment beside tocilizumab whereas, the second group (n = 50) received only standard protocol (steroid, oxygen and antimicrobials). Results: There was no significant difference in mean age between group A (tocilizumab) and group B (standard treatment), 47.29 ±7.09 years versus 48.01 ±9.81 years, respectively (p > 0.05). There was also no significant variation in proportions of males and females between group A and group B, 30 (60.0 %) males and 20 (40.0 %) females versus 27 (54.0 %) males and 23 (46.0 %) females, respectively (p > 0.05). There was also no significant difference in rates of systemic hypertension, diabetes mellitus and asthma between group A and group B (p > 0.05). There was no significant difference in rate of death between group A and group B, 20 (40.0 %) versus 19 (38.0 %), respectively (p > 0.05). Conclusion: In spite of the safety of tocilizumab in patients with severe COVID-19, it is not efficient in reducing mortality rate in comparison with standard treatment protocol. © 2022, ResearchTrentz Academy Publishing Education Services. All rights reserved.
ABSTRACT
BACKGROUND: COVID-19 infection usually causes respiratory distress syndrome. Liver impairment has been reported, there is no clear mechanism for liver damage. Liver damage may be due to other factors, such as a viral infection or inflammations in the liver. Lack of information among the residents of the city of Najaf about the differences between males and females infected with the “Corona Virus” disease (“COVID-19”). AIM: In this study, we focus on the effects of “COVID-19” on liver physiology in 60 (“COVID-19”) patients (20–70 years old). METHODS: Examinations, considering demographic information and clinical findings, show that the patient has liver abnormalities. RESULTS: The result showed an increase in liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), ALP, and TBiL levels in patients with COVID-19 Corona Virus. Male patients had a higher risk of liver enzymes level elevation than females. “TBiL” concentrations were highly increased when compared with control. In critical patients, severe liver cells abnormalities result from “COVID-19”, which requires follow-up and immediate therapeutic intervention. CONCLUSION: Due to its strong relationship with the severity of the injury in “COVID-19”, ALT, AST, ALP, and TBiL, it is expected to be of great importance in the future prediction and diagnosis of infection.
ABSTRACT
The first confirmed COVID-19 case reported in Iraq was in Najaf Governorate on February 2020. Soon later, Iraqi cities have witnessed a significant increase in the reported cases;among them is Diwaniya city in which 13246 total cases were reported on the 25th of September 2020. The cure rate was about 78% (169 deaths and 10676 recovered patients). De-spite the healthcare interventions performed by the medical staff, particularly the public health authorities in Diwaniya city, there have been a dramatically increasing number of reported cas-es. This work aims at introducing comprehensive study and epidemiological characterization of COVID-19 reported cases in Diwaniya governorate. The study involve descriptive analysis of COVID-19 confirmed cases reported in Diwaniya Governorate (24 February 2020 to 25 September 2020). The anal ysi s i nvol ved epi demi ol ogi cal and demographi c characteri zati on of confirmed cases. Data were kindly obtained from the Directorate of Health in Diwaniya. Results and discussion: The highest prevalence was reported in the city center followed by Shamyah district, Al-Hamza district and Afak district, respectively. In terms of gender, about 48% of the confirmed patients were females and about 52% were males (with death rate of about 1.4% 1.8% in females and males, respectively). Although the age in most cases was between 20 and 60 years, the highest incidence (20%) was in age of 30 to 40years. In addition, 8%of reported cases were in children under 15 years old. About 5% of cases were among healthcare workers. Highlighting such findings can enable the community to understand and reconsider COVID-19 spread in Diwaniya, increase the awareness of our community and establish a baseline data for future studies.
ABSTRACT
Background: Covid-19 manifest multisystemic disease affect respiratory, gastrointestinal trac, nervous systems as well as other body systems. baichemical parameters can help in diagnosis and follow up. Methods:130 patients were enrolled in the study ,65 patients of them diagnosed as having COVID-19 infection and other 65 participant were normal ,blood drawn from all of them and CBC,LDH,D-dimer,CRP and ferritin were measured. Results: 65 patients with positive PCR covid -19 infection with mean age (44.2±13.1) and 65 participant as control with negative RT-PCR with mean age (41.6±14.9).patients showing significant decrease in total WBc count and Lymphocytes (P-value:0.0001,0.0001),and significant rise of LDH,DDimer ,CRP and Ferritin levels (P-value:0.004,0.002,0.001,0.0001) Conclusion: Biochemical parameters can be used as a predictor of COVID-19 infections rather than RT-PCR test or strengthen its results. © 2020 EManuscript Technologies. All rights reserved.